STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apc2LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2. (2289 aa)    
Predicted Functional Partners:
Ctnnb1
Catenin beta 1.
   
 0.993
Axin1
Axin-1 isoform X1.
   
 0.985
Axin2
Axin 2.
   
 0.977
Arhgef4
Rho guanine nucleotide exchange factor 4/29.
   
 0.959
ENSCCNP00000004933
Casein kinase I-like isoform X1.
    
 0.956
Csnk1a1
Casein kinase I isoform X1.
    
 0.956
Dvl1
Segment polarity protein dishevelled homolog DVL-1 isoform X1.
    
 0.947
Dvl3
Segment polarity protein dishevelled homolog DVL-3 isoform X1.
    
 0.947
Dvl2
Segment polarity protein dishevelled homolog DVL-2 isoform X1.
    
 0.947
ENSCCNP00000001084
Lymphoid enhancer-binding factor 1.
    
 0.941
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.