STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ezh2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (711 aa)    
Predicted Functional Partners:
Suz12
Polycomb protein SUZ12 isoform X1.
   
 0.999
Eed
Embryonic ectoderm development.
   
 0.998
Jarid2
Protein Jumonji isoform X1.
   
 0.972
ENSCCNP00000006937
DNA (cytosine-5)-methyltransferase 1-like.
   
 0.945
Phf1
PHD finger protein 1 isoform X1.
   
 0.943
Hdac1
Histone deacetylase 1/2.
   
 0.941
Mtf2
Metal-response element-binding transcription factor 2 isoform X1.
   
 0.939
ENSCCNP00000006455
Histone H3.
   
 0.935
ENSCCNP00000002204
annotation not available
   
 0.913
Rbbp7
Histone-binding protein RBBP7.
   
 0.904
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.