STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HttLOW QUALITY PROTEIN: huntingtin. (2785 aa)    
Predicted Functional Partners:
Hip1
Huntingtin interacting protein 1.
    
 0.959
Itpr1
Inositol 1,4,5-trisphosphate receptor type 1 isoform X1.
    
 0.956
Rest
RE1-silencing transcription factor.
    
 0.941
Ap2a2
AP-2 complex subunit alpha-2 isoform X1.
    
 0.939
Ap2b1
AP-2 complex subunit beta isoform X1.
   
 0.935
Ppargc1a
Alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha.
   
 0.934
Ap2m1
AP-2 complex subunit mu isoform X1.
    
  0.932
Ap2s1
AP-2 complex subunit sigma-1.
     
  0.928
Becn1
Beclin-1 isoform X1.
    
 0.928
Gm38100
Beclin-2.
    
 0.922
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.