STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCCNP00000009755E3 ubiquitin-protein ligase SMURF2 isoform X1. (54 aa)    
Predicted Functional Partners:
Smad7
Mothers against decapentaplegic homolog 7 isoform X1.
    
 0.952
Smad2
LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 2-like.
    
 0.892
Tgfbr1
TGF-beta receptor type-1.
    
 0.864
Smad3
Mothers against decapentaplegic homolog 3 isoform X1.
    
 0.848
Uba52
Ubiquitin-60S ribosomal protein L40 isoform X1.
    
 0.835
ENSCCNP00000008906
annotation not available
    
 0.787
Rps27a
Ubiquitin-small subunit ribosomal protein S27Ae.
    
 0.787
Smad4
Mothers against decapentaplegic homolog 4 isoform X1.
   
 0.778
Smad5
Mothers against decapentaplegic homolog 5 isoform X1.
    
 0.680
Ubb
LOW QUALITY PROTEIN: polyubiquitin-B.
    
 0.670
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.