STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sorcs2VPS10 domain-containing receptor SorCS2. (1159 aa)    
Predicted Functional Partners:
Gak
Cyclin-G-associated kinase isoform X1.
   
 
 0.883
Ngf
LOW QUALITY PROTEIN: beta-nerve growth factor.
    
 
 0.882
Dnajc6
Putative tyrosine-protein phosphatase auxilin isoform X1.
     
 0.609
Bdnf
LOW QUALITY PROTEIN: brain-derived neurotrophic factor.
    
 
 0.576
Igf2r
LOW QUALITY PROTEIN: cation-independent mannose-6-phosphate receptor-like.
    
 0.574
Sh3tc1
SH3 domain and tetratricopeptide repeat-containing protein 1.
      
 0.572
Hivep2
Human immunodeficiency virus type I enhancer-binding protein.
    
 
 0.572
Cltc
Clathrin heavy chain 1 isoform X1.
    
 0.554
Cmip
C-Maf-inducing protein isoform X1.
      
 0.539
Nts
Neurotensin/neuromedin N.
    
 
 0.532
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.