Tab3 protein (Castor canadensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Tab3

TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (677 aa)

Predicted Functional Partners:

Map3k7

0.998

Traf6

0.995

Tab1

0.992

Tab2

0.984

Ikbkg

0.981

Irak1

0.974

Ripk2

0.970

Ikbkb

0.966

Chuk

0.963

Traf2

0.959

Your Current Organism:

Castor canadensis

NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Chuk	Ikbkb	ENSCCNP00000010625	ENSCCNP00000009586	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	0.999
Chuk	Ikbkg	ENSCCNP00000010625	ENSCCNP00000002184	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	Inhibitor of kappaB kinase gamma.	0.995
Chuk	Irak1	ENSCCNP00000010625	ENSCCNP00000002948	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	Interleukin-1 receptor-associated kinase 1 isoform X1.	0.982
Chuk	Map3k7	ENSCCNP00000010625	ENSCCNP00000009942	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	Mitogen-activated protein kinase kinase kinase 7 isoform X1.	0.984
Chuk	Tab1	ENSCCNP00000010625	ENSCCNP00000001707	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.	0.975
Chuk	Tab2	ENSCCNP00000010625	ENSCCNP00000008467	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.	0.962
Chuk	Tab3	ENSCCNP00000010625	ENSCCNP00000011035	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3.	0.963
Chuk	Traf2	ENSCCNP00000010625	ENSCCNP00000022087	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	TNF receptor-associated factor 2 isoform X1.	0.982
Chuk	Traf6	ENSCCNP00000010625	ENSCCNP00000030232	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	TNF receptor-associated factor 6.	0.990
Ikbkb	Chuk	ENSCCNP00000009586	ENSCCNP00000010625	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	0.999
Ikbkb	Ikbkg	ENSCCNP00000009586	ENSCCNP00000002184	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	Inhibitor of kappaB kinase gamma.	0.996
Ikbkb	Irak1	ENSCCNP00000009586	ENSCCNP00000002948	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	Interleukin-1 receptor-associated kinase 1 isoform X1.	0.597
Ikbkb	Map3k7	ENSCCNP00000009586	ENSCCNP00000009942	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	Mitogen-activated protein kinase kinase kinase 7 isoform X1.	0.990
Ikbkb	Ripk2	ENSCCNP00000009586	ENSCCNP00000032795	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	Receptor-interacting serine/threonine-protein kinase 2 isoform X1.	0.408
Ikbkb	Tab1	ENSCCNP00000009586	ENSCCNP00000001707	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.	0.972
Ikbkb	Tab2	ENSCCNP00000009586	ENSCCNP00000008467	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.	0.961
Ikbkb	Tab3	ENSCCNP00000009586	ENSCCNP00000011035	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3.	0.966
Ikbkb	Traf2	ENSCCNP00000009586	ENSCCNP00000022087	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	TNF receptor-associated factor 2 isoform X1.	0.985
Ikbkb	Traf6	ENSCCNP00000009586	ENSCCNP00000030232	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	TNF receptor-associated factor 6.	0.989
Ikbkg	Chuk	ENSCCNP00000002184	ENSCCNP00000010625	Inhibitor of kappaB kinase gamma.	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	0.995