STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fbxl8F-box and leucine-rich repeat protein 8. (374 aa)    
Predicted Functional Partners:
Cul1
Cullin 1.
    
 0.722
Tmem208
Transmembrane protein 208 isoform X1.
      
 0.613
Nedd8
Ubiquitin-like protein Nedd8.
    
 0.607
Cul3
Cullin-3 isoform X1.
    
 0.594
ENSCCNP00000001750
annotation not available
   
 0.583
Skp1
S-phase kinase-associated protein 1.
   
 0.583
ENSCCNP00000007981
annotation not available
   
 0.583
ENSCCNP00000027338
annotation not available
   
 0.583
ENSCCNP00000030366
annotation not available
   
 0.583
Cacna2d2
Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1.
   
  
 0.568
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.