STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mmp17Matrix metalloproteinase-17 (membrane-inserted). (573 aa)    
Predicted Functional Partners:
Hbegf
LOW QUALITY PROTEIN: proheparin-binding EGF-like growth factor.
   
 0.923
Gnai2
Guanine nucleotide-binding protein G(i) subunit alpha-2.
     
 0.902
Gnai1
Guanine nucleotide-binding protein G(i) subunit alpha-1.
     
 0.902
Gnai3
Guanine nucleotide-binding protein G(i) subunit alpha.
     
 0.902
Timp2
Metalloproteinase inhibitor 2.
   
 0.727
Timp3
Metalloproteinase inhibitor 3.
   
 0.644
Timp1
Metalloproteinase inhibitor 1.
   
 0.605
Mmp13
Matrix metalloproteinase-13 (collagenase 3).
  
0.551
Furin
Furin.
    
 0.464
Timp4
Metalloproteinase inhibitor 4.
    
 0.454
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.