STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nsd2Histone-lysine N-methyltransferase NSD2 isoform X1. (1365 aa)    
Predicted Functional Partners:
Brd4
Bromodomain-containing protein 4 isoform X1.
   
 
 0.720
ENSCCNP00000023058
Histone H2A type 1-like.
    
  0.685
Camkmt
Calmodulin-lysine N-methyltransferase.
     
 0.681
Plod2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
    
 0.676
Plod3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 isoform X1.
    
 0.676
Plod1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
    
 0.676
ENSCCNP00000006455
Histone H3.
   
 0.669
Mre11a
Double-strand break repair protein MRE11A isoform X1.
   
 0.660
Tp53bp1
Tumor suppressor p53-binding protein 1 isoform X1.
    
 0.644
Eed
Embryonic ectoderm development.
   
 0.632
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.