STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Jak2Tyrosine-protein kinase JAK2 isoform X1. (1132 aa)    
Predicted Functional Partners:
Stat3
Signal transducer and activator of transcription 3 isoform X1.
   
 0.997
Epor
Erythropoietin receptor.
    
 0.996
Socs3
Suppressor of cytokine signaling 3.
   
 0.996
Lepr
Leptin receptor.
    
 0.994
Ghr
Growth hormone receptor isoform X1.
    
 0.993
Stat1
Signal transducer and activator of transcription 1-alpha/beta.
   
 0.992
Ifngr2
Interferon gamma receptor 2.
   
 0.991
Jak1
Tyrosine-protein kinase JAK1 isoform X1.
   
0.989
Il12rb2
Interleukin-12 receptor subunit beta-2.
    
 0.988
Prlr
Prolactin receptor isoform X1.
    
 0.987
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.