STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NgefNeuronal guanine nucleotide exchange factor. (129 aa)    
Predicted Functional Partners:
Epha4
LOW QUALITY PROTEIN: ephrin type-A receptor 4-like.
    
 0.971
Epha1
Ephrin type-A receptor 1.
    
 0.958
Cdc42
Cell division control protein 42 homolog.
    
 0.946
4930544G11Rik
Transforming protein RhoA-like isoform X1.
    
 0.944
Epha3
Ephrin type-A receptor 3 isoform X1.
    
 0.932
Rhoa
Ras homolog gene family, member A.
    
  0.928
Rac3
Ras-related C3 botulinum toxin substrate 3 isoform X1.
    
 0.924
Rac2
Ras-related C3 botulinum toxin substrate 2 isoform X1.
    
 0.924
ENSCCNP00000010582
Ephrin type-A receptor 7-like.
    
 0.920
Ephb2
LOW QUALITY PROTEIN: ephrin type-B receptor 2.
    
 0.920
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.