STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Aak1LOW QUALITY PROTEIN: AP2-associated protein kinase 1. (915 aa)    
Predicted Functional Partners:
Ap2m1
AP-2 complex subunit mu isoform X1.
    
 0.886
ENSCCNP00000025069
Epidermal growth factor receptor substrate 15-like.
   
 0.848
Reps1
RalBP1-associated Eps domain-containing protein 1 isoform X1.
    
 0.846
Gak
Cyclin-G-associated kinase isoform X1.
   
0.843
Dnajc6
Putative tyrosine-protein phosphatase auxilin isoform X1.
 
 
 0.843
Ap2s1
AP-2 complex subunit sigma-1.
    
 0.816
Eps15l1
Epidermal growth factor receptor substrate 15-like 1 isoform X1.
   
 0.807
Reps2
RalBP1-associated Eps domain-containing protein 2 isoform X1.
    
 0.804
Picalm
Phosphatidylinositol-binding clathrin assembly protein isoform X1.
    
 0.740
Snap91
Clathrin coat assembly protein AP180 isoform X1.
    
 0.740
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.