STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pik3r2Phosphoinositide-3-kinase regulatory subunit 2. (625 aa)    
Predicted Functional Partners:
Pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
   
 0.979
Pik3ca
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1.
   
 0.975
Pik3cd
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1.
   
 0.947
Pik3r1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
  
 
0.930
Pik3cg
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform.
    
 0.907
Pik3r3
Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.
  
 
0.879
Egfr
Epidermal growth factor receptor isoform X1.
    
 0.788
Grb2
Growth factor receptor-bound protein 2 isoform X1.
    
0.787
Erbb3
Receptor tyrosine-protein kinase erbB-3.
    
 0.708
Gab1
GRB2-associated-binding protein 1 isoform X1.
    
 0.701
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.