STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp2r1Vitamin D 25-hydroxylase. (501 aa)    
Predicted Functional Partners:
Cyp27b1
Calcidiol 1-monooxygenase (25-hydroxyvitamin D3 1alpha-hydroxylase).
  
0.948
Cyp24a1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial isoform X1.
  
0.930
Dhcr7
7-dehydrocholesterol reductase.
   
 0.657
Gc
Vitamin D-binding protein.
   
  
 0.598
Cyp7a1
Cholesterol 7-alpha-monooxygenase.
  
  
 0.569
Aasdh
LOW QUALITY PROTEIN: acyl-CoA synthetase family member 4.
  
 0.549
Tbxas1
Thromboxane-A synthase.
  
 0.546
Cyp27a1
LOW QUALITY PROTEIN: sterol 26-hydroxylase, mitochondrial.
  
 
0.508
Vdr
Vitamin D3 receptor.
   
 0.496
Nadsyn1
Glutamine-dependent NAD(+) synthetase.
   
  
 0.493
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.