STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Herc4Probable E3 ubiquitin-protein ligase HERC4. (959 aa)    
Predicted Functional Partners:
ENSCCNP00000015936
Probable E3 ubiquitin-protein ligase HERC4.
 
    
 0.905
Isg15
Ubiquitin cross-reactive protein.
   
 0.594
Ube2l6
Ubiquitin/ISG15-conjugating enzyme E2 L6 isoform X1.
   
 0.585
Pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta.
      
 0.524
Trip12-2
E3 ubiquitin-protein ligase TRIP12 isoform X1.
   
 
 0.483
Trip12
LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIP12-like.
   
 
0.483
ENSCCNP00000029050
E3 ubiquitin-protein ligase TRIP12-like isoform X1.
   
 
 0.483
Psmd4
LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 4.
    
 
 0.461
Ifih1
Interferon-induced helicase C domain-containing protein 1.
   
 
 0.454
Mypn
Myopalladin.
      
 0.448
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.