STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HckTyrosine-protein kinase HCK isoform X1. (524 aa)    
Predicted Functional Partners:
Lyn
Tyrosine-protein kinase Lyn isoform X1.
  
0.961
Ptk2b
Protein-tyrosine kinase 2-beta isoform X1.
   
0.960
Ptk2
Focal adhesion kinase 1 isoform X1.
   
0.960
Pik3r1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
    
 0.951
Shc3
SHC-transforming protein 3.
   
 0.946
Shc1
LOW QUALITY PROTEIN: SHC-transforming protein 1.
   
 0.946
Pik3ca
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1.
   
 0.946
Pik3cd
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1.
   
 0.945
Pik3r3
Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.
    
 0.943
Src
Proto-oncogene tyrosine-protein kinase Src.
  
 
0.936
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.