STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OsmOncostatin-M isoform X1. (238 aa)    
Predicted Functional Partners:
Lifr
Leukemia inhibitory factor receptor.
    
 0.984
Osmr
Oncostatin-M-specific receptor subunit beta isoform X1.
    
 0.977
Il6st
Interleukin-6 receptor subunit beta.
    
 0.954
Jak2
Tyrosine-protein kinase JAK2 isoform X1.
     
 0.865
Jak1
Tyrosine-protein kinase JAK1 isoform X1.
     
 0.857
Il27ra
Interleukin-27 receptor subunit alpha.
    
 0.831
Il12rb2
Interleukin-12 receptor subunit beta-2.
    
 0.831
Csf3r
Granulocyte colony-stimulating factor receptor isoform X1.
   
 0.793
Lif
Leukemia inhibitory factor.
   
 
 0.757
Il6r
Interleukin-6 receptor subunit alpha.
     
 0.724
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.