STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Frat2Frequently rearranged in advanced T-cell lymphomas 2. (232 aa)    
Predicted Functional Partners:
Dvl1
Segment polarity protein dishevelled homolog DVL-1 isoform X1.
    
 0.927
Dvl3
Segment polarity protein dishevelled homolog DVL-3 isoform X1.
    
 0.914
Dvl2
Segment polarity protein dishevelled homolog DVL-2 isoform X1.
    
 0.914
Frat1
Frequently rearranged in advanced T-cell lymphomas 1.
  
  
 
0.901
Gsk3a
Glycogen synthase kinase 3 alpha.
    
 0.894
Axin1
Axin-1 isoform X1.
    
 0.478
Ctnnb1
Catenin beta 1.
     
 0.429
Apc2
LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.
     
 0.428
Apc
Adenomatous polyposis coli protein isoform X1.
     
 0.408
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.