STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Espl1Separase. (2112 aa)    
Predicted Functional Partners:
Smc3
Structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6).
   
 0.987
Rad21
Double-strand-break repair protein rad21 homolog.
   
 0.986
Plk1
Serine/threonine-protein kinase PLK1.
   
 0.979
Smc1a
Structural maintenance of chromosomes protein 1A isoform X1.
   
 0.978
ENSCCNP00000026116
Structural maintenance of chromosomes protein 1B-like.
   
 0.977
Stag2
Cohesin complex subunit SA-1/2.
    
 0.966
Cdc20
Cell division cycle 20, cofactor of APC complex.
   
 0.962
ENSCCNP00000002440
Mitotic checkpoint serine/threonine-protein kinase BUB1-like.
   
 
 0.960
Stag1
Cohesin subunit SA-1 isoform X1.
    
 0.960
Cdca8
Borealin.
   
 
 0.954
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.