STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gadd45aGrowth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa)    
Predicted Functional Partners:
Pcna
Proliferating cell nuclear antigen.
    
  0.985
Map3k4
Mitogen-activated protein kinase kinase kinase 4 isoform X1.
    
 0.975
Trp53
Cellular tumor antigen p53 isoform X1.
     
 0.960
Cdk1
LOW QUALITY PROTEIN: cyclin-dependent kinase 1-like.
    
 0.958
Ccnb2
G2/mitotic-specific cyclin-B2.
    
 0.929
Gadd45b
Growth arrest and DNA damage-inducible protein GADD45 beta.
  
0.923
Gadd45g
Growth arrest and DNA damage-inducible protein GADD45 gamma isoform X1.
  
0.922
Aurka
Aurora kinase A isoform X1.
    
 0.707
Cdkn1a
Cyclin-dependent kinase inhibitor 1A.
   
 
 0.697
Gadd45gip1
LOW QUALITY PROTEIN: growth arrest and DNA damage-inducible proteins-interacting protein 1.
    
 
 0.695
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.