STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MfrpMembrane frizzled-related protein isoform X1. (577 aa)    
Predicted Functional Partners:
Gsk3a
Glycogen synthase kinase 3 alpha.
    
 0.753
Met
Hepatocyte growth factor receptor isoform X1.
    
 0.711
Mst1r
Macrophage-stimulating protein receptor.
    
 0.711
Amn
Amnionless.
   
 0.601
Tnfaip6
Tumor necrosis factor-inducible gene 6 protein.
    
0.575
Ptk7
Inactive tyrosine-protein kinase 7.
    
 0.549
ENSCCNP00000010977
annotation not available
   
 0.524
ENSCCNP00000019524
Intersectin-2-like isoform X1.
   
 0.524
Itsn2
Intersectin 2.
   
 0.524
Ripk4
Receptor-interacting serine/threonine-protein kinase 4.
    
 0.518
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.