STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Capn2LOW QUALITY PROTEIN: calpain-2 catalytic subunit. (699 aa)    
Predicted Functional Partners:
Capn1
LOW QUALITY PROTEIN: calpain-1 catalytic subunit.
  
0.954
Capns1
LOW QUALITY PROTEIN: calpain small subunit 1.
   
0.933
Tln1
Talin-1 isoform X1.
   
 0.925
Tln2
Talin-2 isoform X1.
   
 0.920
Bid
BH3-interacting domain death agonist isoform X1.
   
 0.912
Bak1
Bcl-2 homologous antagonist/killer.
   
 0.905
Il1a
Interleukin 1 alpha.
   
 
 0.904
Bax
Apoptosis regulator BAX.
    
 0.901
ENSCCNP00000002824
LOW QUALITY PROTEIN: calpastatin-like.
   
 0.875
ENSCCNP00000033135
Calpastatin-like.
   
 0.875
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.