STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Map3k14Mitogen-activated protein kinase kinase kinase 14 isoform X1. (940 aa)    
Predicted Functional Partners:
Chuk
Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.
   
0.994
Traf3
TNF receptor-associated factor 3 isoform X1.
   
 0.992
Traf2
TNF receptor-associated factor 2 isoform X1.
   
 0.990
Ikbkb
Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.
   
0.988
Traf6
TNF receptor-associated factor 6.
   
 0.970
Map3k8
Mitogen-activated protein kinase kinase kinase 8 isoform X1.
    
0.969
Ltbr
LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 3.
   
 0.959
Map3k7
Mitogen-activated protein kinase kinase kinase 7 isoform X1.
   
0.920
Tab1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.
    
 0.916
Tab2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.
   
 
 0.902
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
Server load: low (22%) [HD]