STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Il2Interleukin 2. (155 aa)    
Predicted Functional Partners:
Il2rb
Interleukin-2 receptor subunit beta isoform X1.
    
 0.996
Il2rg
Cytokine receptor common subunit gamma.
    
 0.995
Il2ra
Interleukin 2 receptor, alpha chain.
    
 0.975
Jak1
Tyrosine-protein kinase JAK1 isoform X1.
     
 0.970
Foxp3
Forkhead box P3.
   
 0.898
Il15ra
Interleukin-15 receptor subunit alpha.
     
 0.895
Il5
Interleukin 5.
   
 
 0.879
Il6
Interleukin 6.
      
 0.861
Il7
Interleukin 7.
      
 0.858
Il17a
Interleukin 17A.
   
 
 0.858
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.