STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SpoplSpeckle-type POZ protein-like isoform X1. (392 aa)    
Predicted Functional Partners:
Cul3
Cullin-3 isoform X1.
   
 0.996
Gli1
Zinc finger protein GLI1 isoform X1.
   
 0.976
Gli2
Zinc finger protein GLI2.
   
 0.974
Gli3
Transcriptional activator GLI3 isoform X1.
   
 0.973
Spop
Speckle-type POZ protein.
  
 
0.966
Sufu
Suppressor of fused homolog isoform X1.
     
 0.942
Cul1
Cullin 1.
   
 0.890
Cacul1
CDK2-associated and cullin domain-containing protein 1.
   
 0.818
Rbx1
E3 ubiquitin-protein ligase RBX1.
    
 0.812
Ube2i
Ubiquitin-conjugating enzyme E2 I.
    
 
 0.811
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.