STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ntf3Neurotrophin-3 isoform X1. (270 aa)    
Predicted Functional Partners:
Ntrk2
BDNF/NT-3 growth factors receptor isoform X1.
    
 0.989
Ntrk1
High affinity nerve growth factor receptor isoform X1.
    
 0.989
Ntrk3
Neurotrophic tyrosine kinase, receptor, type 3.
    
 0.916
Ngfr
Tumor necrosis factor receptor superfamily member 16.
     
  0.900
Bdnf
LOW QUALITY PROTEIN: brain-derived neurotrophic factor.
  
 
0.775
Insr
LOW QUALITY PROTEIN: insulin receptor.
    
 0.724
Igf1r
Insulin-like growth factor 1 receptor.
    
 0.724
Epha2
LOW QUALITY PROTEIN: ephrin type-A receptor 2.
    
 0.717
Met
Hepatocyte growth factor receptor isoform X1.
    
 0.711
Tek
Endothelial-specific receptor tyrosine kinase.
     
 0.695
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.