STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Notch3LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 3. (2316 aa)    
Predicted Functional Partners:
Rbpj
Recombining binding protein suppressor of hairless isoform X1.
    
 0.995
Jag2
Protein jagged-2 isoform X1.
   
0.990
Jag1
Protein jagged-1 isoform X1.
   
0.989
Dll4
Delta-like protein 4 isoform X1.
    
0.988
Maml1
LOW QUALITY PROTEIN: mastermind-like protein 1.
   
 0.971
Maml3
Mastermind-like protein 3.
    
 0.960
Notch1
Neurogenic locus notch homolog protein 1.
  
0.945
Rbpjl
Recombining binding protein suppressor of hairless-like protein.
    
 0.945
Notch2
Neurogenic locus notch homolog protein 2 isoform X1.
  
 
0.942
Maml2
Mastermind-like protein 2.
    
 0.940
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.