Btla protein (Castor canadensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Btla

B- and T-lymphocyte attenuator. (249 aa)

Predicted Functional Partners:

Tnfrsf14

0.974

Ptpn11

0.827

Vtcn1

0.696

Lag3

0.670

Cd40

0.652

Cd27

0.644

Ptpn6

0.636

Tnfrsf11b

0.625

Tnfrsf18

0.625

Ltbr

0.625

Your Current Organism:

Castor canadensis

NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Btla	Cd27	ENSCCNP00000027652	ENSCCNP00000025939	B- and T-lymphocyte attenuator.	Tumor necrosis factor receptor superfamily member 7.	0.644
Btla	Cd40	ENSCCNP00000027652	ENSCCNP00000023804	B- and T-lymphocyte attenuator.	Tumor necrosis factor receptor superfamily member 5 isoform X1.	0.652
Btla	Lag3	ENSCCNP00000027652	ENSCCNP00000026102	B- and T-lymphocyte attenuator.	Lymphocyte-activation gene 3.	0.670
Btla	Ltbr	ENSCCNP00000027652	ENSCCNP00000025935	B- and T-lymphocyte attenuator.	LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 3.	0.625
Btla	Ptpn11	ENSCCNP00000027652	ENSCCNP00000023133	B- and T-lymphocyte attenuator.	Tyrosine-protein phosphatase non-receptor type 11 isoform X1.	0.827
Btla	Ptpn6	ENSCCNP00000027652	ENSCCNP00000026221	B- and T-lymphocyte attenuator.	Tyrosine-protein phosphatase non-receptor type 6 isoform X1.	0.636
Btla	Tnfrsf11b	ENSCCNP00000027652	ENSCCNP00000005734	B- and T-lymphocyte attenuator.	Tumor necrosis factor receptor superfamily member 11B.	0.625
Btla	Tnfrsf14	ENSCCNP00000027652	ENSCCNP00000003420	B- and T-lymphocyte attenuator.	Tumor necrosis factor receptor superfamily member 14 isoform X1.	0.974
Btla	Tnfrsf18	ENSCCNP00000027652	ENSCCNP00000010949	B- and T-lymphocyte attenuator.	Tumor necrosis factor receptor superfamily member 18.	0.625
Btla	Vtcn1	ENSCCNP00000027652	ENSCCNP00000005867	B- and T-lymphocyte attenuator.	V-set domain-containing T-cell activation inhibitor 1.	0.696
Cd27	Btla	ENSCCNP00000025939	ENSCCNP00000027652	Tumor necrosis factor receptor superfamily member 7.	B- and T-lymphocyte attenuator.	0.644
Cd27	Cd40	ENSCCNP00000025939	ENSCCNP00000023804	Tumor necrosis factor receptor superfamily member 7.	Tumor necrosis factor receptor superfamily member 5 isoform X1.	0.726
Cd27	Lag3	ENSCCNP00000025939	ENSCCNP00000026102	Tumor necrosis factor receptor superfamily member 7.	Lymphocyte-activation gene 3.	0.609
Cd40	Btla	ENSCCNP00000023804	ENSCCNP00000027652	Tumor necrosis factor receptor superfamily member 5 isoform X1.	B- and T-lymphocyte attenuator.	0.652
Cd40	Cd27	ENSCCNP00000023804	ENSCCNP00000025939	Tumor necrosis factor receptor superfamily member 5 isoform X1.	Tumor necrosis factor receptor superfamily member 7.	0.726
Cd40	Ltbr	ENSCCNP00000023804	ENSCCNP00000025935	Tumor necrosis factor receptor superfamily member 5 isoform X1.	LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 3.	0.401
Lag3	Btla	ENSCCNP00000026102	ENSCCNP00000027652	Lymphocyte-activation gene 3.	B- and T-lymphocyte attenuator.	0.670
Lag3	Cd27	ENSCCNP00000026102	ENSCCNP00000025939	Lymphocyte-activation gene 3.	Tumor necrosis factor receptor superfamily member 7.	0.609
Ltbr	Btla	ENSCCNP00000025935	ENSCCNP00000027652	LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 3.	B- and T-lymphocyte attenuator.	0.625
Ltbr	Cd40	ENSCCNP00000025935	ENSCCNP00000023804	LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 3.	Tumor necrosis factor receptor superfamily member 5 isoform X1.	0.401