STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Grk2G protein-coupled receptor kinase 2. (651 aa)    
Predicted Functional Partners:
Gna11
Guanine nucleotide-binding protein subunit alpha-11 isoform X1.
    
 0.832
Arrb2
Beta-arrestin-2 isoform X1.
   
 0.759
Git1
LOW QUALITY PROTEIN: ARF GTPase-activating protein GIT1.
    
 
 0.738
Rho
Rhodopsin.
   
 0.724
Arrb1
Beta-arrestin-1 isoform X1.
   
 0.718
Gna14
Guanine nucleotide-binding protein subunit alpha-14.
    
 0.714
Smo
Smoothened homolog isoform X1.
    
 0.693
Gnb2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.
   
 0.684
Adrb2
Adrenergic receptor beta-2.
   
 0.677
Gnb1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.
   
 0.671
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.