STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Stat3Signal transducer and activator of transcription 3 isoform X1. (770 aa)    
Predicted Functional Partners:
Jak2
Tyrosine-protein kinase JAK2 isoform X1.
   
 0.997
Stat1
Signal transducer and activator of transcription 1-alpha/beta.
  
0.996
Jak1
Tyrosine-protein kinase JAK1 isoform X1.
   
 0.991
Ep300
Histone acetyltransferase p300.
    
 0.986
Src
Proto-oncogene tyrosine-protein kinase Src.
   
 0.983
Il6r
Interleukin-6 receptor subunit alpha.
   
 0.982
Tyk2
Non-receptor tyrosine-protein kinase TYK2.
   
 0.973
Stat5b
Signal transducer and activator of transcription 5B.
   
0.969
Stat5a
Signal transducer and activator of transcription 5A.
   
0.969
Socs3
Suppressor of cytokine signaling 3.
   
 0.968
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.