STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Socs7LOW QUALITY PROTEIN: suppressor of cytokine signaling 7. (577 aa)    
Predicted Functional Partners:
Tyk2
Non-receptor tyrosine-protein kinase TYK2.
    
 0.934
Jak2
Tyrosine-protein kinase JAK2 isoform X1.
    
 0.934
Jak1
Tyrosine-protein kinase JAK1 isoform X1.
    
 0.934
Cul5
Cullin 5.
   
 0.821
Stat3
Signal transducer and activator of transcription 3 isoform X1.
   
 0.759
Stat1
Signal transducer and activator of transcription 1-alpha/beta.
   
 0.757
Stat5b
Signal transducer and activator of transcription 5B.
   
 0.757
Stat5a
Signal transducer and activator of transcription 5A.
   
 0.757
ENSCCNP00000008185
annotation not available
    
 0.754
Eloc
Transcription elongation factor B polypeptide 1 isoform X1.
    
 0.754
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.