STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MertkC-mer proto-oncogene tyrosine kinase. (832 aa)    
Predicted Functional Partners:
Pros1
Vitamin K-dependent protein S.
     
 0.838
Gas6
Growth arrest-specific protein 6.
    
 0.792
Lgals3
LOW QUALITY PROTEIN: galectin-3.
   
 
 0.606
Rpe65
Retinoid isomerohydrolase / lutein isomerase.
   
 
 0.596
Mib2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.586
Tab1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.
   
 0.572
Traf6
TNF receptor-associated factor 6.
   
 0.566
Cd247
CD247 antigen.
   
 0.538
Fadd
FAS-associated death domain protein.
   
 0.527
Tradd
Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1.
   
 0.526
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.