STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PoleLOW QUALITY PROTEIN: DNA polymerase epsilon catalytic subunit A. (691 aa)    
Predicted Functional Partners:
Pole2
DNA polymerase epsilon subunit 2.
   
 0.999
Pole4
DNA polymerase epsilon subunit 4.
    
 0.995
Pole3
DNA polymerase epsilon subunit 3.
   
 0.995
Mcm2
DNA replication licensing factor MCM2.
   
 0.950
Mcm5
DNA replication licensing factor MCM5.
   
 0.944
Mcm3
DNA replication licensing factor MCM3.
   
 0.942
Mcm4
DNA replication licensing factor MCM4.
   
 0.939
Pola1
DNA polymerase alpha catalytic subunit isoform X1.
   
 0.938
ENSCCNP00000028443
annotation not available
 
     0.937
Cdc45
Cell division control protein 45 homolog isoform X1.
   
 0.936
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.