STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp21a1Steroid 21-hydroxylase isoform X1. (490 aa)    
Predicted Functional Partners:
Hsd11b2
Corticosteroid 11-beta-dehydrogenase isozyme 2.
   
 
 0.949
ENSCCNP00000014465
LOW QUALITY PROTEIN: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like.
   
 0.945
ENSCCNP00000014492
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like isoform X1.
   
 0.945
Cyp11a1
Cholesterol side-chain cleavage enzyme, mitochondrial.
  
0.942
ENSCCNP00000028923
LOW QUALITY PROTEIN: cytochrome P450 11B2, mitochondrial-like.
  
0.942
Cyp7b1
25/26-hydroxycholesterol 7alpha-hydroxylase.
  
  
 0.934
Hsd11b1
Corticosteroid 11-beta-dehydrogenase isozyme 1.
   
 0.930
Cyp17a1
Steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase.
  
 
0.925
Srd5a1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X1.
     
 0.925
Hsd11b1l
Hydroxysteroid 11-beta-dehydrogenase 1-like protein.
   
 
 0.918
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.