STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ptk6Protein tyrosine kinase 6. (451 aa)    
Predicted Functional Partners:
Stap2
Signal-transducing adaptor protein 2.
   
 0.848
Khdrbs1
KH domain-containing, RNA-binding, signal transduction-associated protein 1.
    
 0.840
Bcar1
Breast cancer anti-estrogen resistance protein 1 isoform X1.
   
 0.778
Egfr
Epidermal growth factor receptor isoform X1.
    
0.760
Gpnmb
Transmembrane glycoprotein NMB.
   
 0.706
ENSCCNP00000001126
annotation not available
    
 0.697
Cbl
E3 ubiquitin-protein ligase CBL isoform X1.
    
 0.697
ENSCCNP00000004562
Proto-oncogene tyrosine-protein kinase receptor Ret-like.
 
  
 0.691
Lyn
Tyrosine-protein kinase Lyn isoform X1.
  
0.683
Ptpn1
Tyrosine-protein phosphatase non-receptor type 1 isoform X1.
   
 0.676
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.