STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Col4a3Collagen alpha-3(IV) chain isoform X1. (1669 aa)    
Predicted Functional Partners:
Itgav
LOW QUALITY PROTEIN: integrin alpha-V.
    
 0.925
Itga1
Integrin alpha-1 isoform X1.
   
 0.793
Col4a2
Collagen alpha-2(IV) chain.
  
0.767
Itga3
Integrin alpha-3 isoform X1.
    
 0.745
Itgb1
Integrin beta-1 isoform X1.
    
 0.739
Itgb3
Integrin beta-3 isoform X1.
   
 0.738
Itgb4
Integrin beta-4 isoform X1.
   
 0.737
Itga11
Integrin alpha 11.
   
 0.715
Itgb6
Integrin beta-6 isoform X1.
   
 0.715
Itgb5
LOW QUALITY PROTEIN: integrin beta-5-like.
    
 0.713
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.