STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rnf138E3 ubiquitin-protein ligase RNF138 isoform X1. (248 aa)    
Predicted Functional Partners:
Suclg1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial.
  
 0.696
Fh
Fumarate hydratase, mitochondrial.
  
 0.670
ENSCCNP00000010214
annotation not available
  
 0.627
ENSCCNP00000013023
annotation not available
  
 0.627
Cs
Citrate synthase, mitochondrial.
  
 0.627
Aldh18a1
Delta-1-pyrroline-5-carboxylate synthetase.
     
 0.598
Idh1
Isocitrate dehydrogenase [NADP] cytoplasmic.
  
 
 0.586
Idh2
Isocitrate dehydrogenase [NADP], mitochondrial.
  
 
 0.586
ENSCCNP00000030420
LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase HERC2-like.
      
 0.569
Pcx
Pyruvate carboxylase, mitochondrial isoform X1.
   
 0.562
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.