STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCCNP00000032875Lanosterol 14-alpha demethylase. (503 aa)    
Predicted Functional Partners:
Lss
Lanosterol synthase isoform X1.
   
 0.999
Hsd17b7
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.
   
 
 0.990
Lbr
Delta14-sterol reductase (lamin-B receptor).
   
 0.990
Dhcr24
Delta(24)-sterol reductase.
   
 0.987
Sqle
Squalene monooxygenase.
  
 0.987
Erg28
Probable ergosterol biosynthetic protein 28.
   
 
 0.986
Sigmar1
Sigma non-opioid intracellular receptor 1 isoform X1.
   
 
 0.982
Msmo1
Methylsterol monooxygenase 1.
   
 0.973
Ch25h
Cholesterol 25-hydroxylase.
   
 0.973
Nsdhl
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating.
 
 
 0.972
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.