STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arhgef7Rho guanine nucleotide exchange factor (GEF7). (780 aa)    
Predicted Functional Partners:
Git2
G protein-coupled receptor kinase interactor 2.
    
 0.933
Git1
LOW QUALITY PROTEIN: ARF GTPase-activating protein GIT1.
    
 0.911
Pak2
Serine/threonine-protein kinase PAK 2.
    
 0.846
Pak1
P21 (RAC1) activated kinase 1.
    
 0.834
Cdc42
Cell division control protein 42 homolog.
   
 0.778
ENSCCNP00000013654
annotation not available
   
 0.778
Nck1
Cytoplasmic protein NCK1.
    
0.745
ENSCCNP00000004331
annotation not available
    
 0.741
ENSCCNP00000010977
annotation not available
   
 
 0.702
ENSCCNP00000019524
Intersectin-2-like isoform X1.
   
 
 0.702
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.