STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MaptMicrotubule-associated protein tau. (745 aa)    
Predicted Functional Partners:
Cdk5
Cyclin-dependent-like kinase 5 isoform X1.
    
 
 0.891
Fyn
Tyrosine-protein kinase Fyn isoform X1.
    
 
 0.882
Snca
Alpha-synuclein isoform X1.
   
 
 0.836
Hspa4
LOW QUALITY PROTEIN: heat shock 70 kDa protein 4.
    
 0.806
Stub1
STIP1 homology and U-box containing protein 1.
    
 
 0.804
App
Amyloid beta A4 protein isoform X1.
   
 
 0.795
Ywhaz
14-3-3 protein beta/theta/zeta.
    
 
 0.790
ENSCCNP00000017392
annotation not available
    
 
 0.790
Casp3
Caspase 3.
    
 0.762
Bin1
Bridging integrator 1.
   
 
 0.698
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.