STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2Y460_CIOSACyclic nucleotide-binding domain-containing protein. (321 aa)    
Predicted Functional Partners:
H2Z2I4_CIOSA
Uncharacterized protein.
 
     0.913
H2ZIA3_CIOSA
Aldo_ket_red domain-containing protein.
    
 0.569
H2ZR43_CIOSA
Aldo_ket_red domain-containing protein.
    
 0.569
H2ZL99_CIOSA
Aldo_ket_red domain-containing protein.
    
 0.539
H2YKP3_CIOSA
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 0.523
H2ZFQ2_CIOSA
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 0.523
H2ZPU8_CIOSA
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 0.523
H2YHG2_CIOSA
Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family.
     
 0.443
H2YSX5_CIOSA
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
    
 0.411
H2ZGK1_CIOSA
Uncharacterized protein.
    
 0.401
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.