Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H2Y7Y7_CIOSARING-type domain-containing protein. (159 aa)    
Predicted Functional Partners:
H2ZAW2_CIOSA
Uncharacterized protein.
    
 
 0.888
H2Y716_CIOSA
Uncharacterized protein.
   
 0.863
H2ZDD6_CIOSA
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
 
 0.857
H2YHB1_CIOSA
CYTOSOL_AP domain-containing protein.
      
 0.843
H2Z874_CIOSA
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
    
 0.843
H2Z1B1_CIOSA
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
    
 0.811
H2YYX8_CIOSA
MPN domain-containing protein.
    
 
 0.806
H2YJ94_CIOSA
GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
    
 
 0.753
H2YB47_CIOSA
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.747
H2ZKW7_CIOSA
Uncharacterized protein; Belongs to the AAA ATPase family.
    
 0.733
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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