Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2Y8V4_CIOSASerine/threonine-protein kinase PLK. (549 aa)    
Predicted Functional Partners:
H2YVS1_CIOSA
WD_REPEATS_REGION domain-containing protein.
   
 0.984
H2YPL2_CIOSA
WD_REPEATS_REGION domain-containing protein.
   
 0.982
H2ZC10_CIOSA
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.981
H2YBC2_CIOSA
Rhodanese domain-containing protein.
   
 0.976
H2YY55_CIOSA
Wee1-like protein kinase.
   
 0.973
H2YMC5_CIOSA
Protein kinase domain-containing protein.
   
 0.972
H2YQY6_CIOSA
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.969
H2YPY4_CIOSA
Peptidase C50 domain-containing protein.
   
 0.961
H2Y7X5_CIOSA
Uncharacterized protein.
   
 0.958
H2YJ38_CIOSA
Uncharacterized protein; Belongs to the cyclin family.
   
 0.958
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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