Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
H2YVA8_CIOSAWD_REPEATS_REGION domain-containing protein. (2562 aa)    
Predicted Functional Partners:
H2YSP8_CIOSA
Uncharacterized protein.
   
 
 0.960
H2YGQ3_CIOSA
Uncharacterized protein.
    
 
 0.935
H2Z5G6_CIOSA
Uncharacterized protein.
    
 
 0.935
H2YZ53_CIOSA
Uncharacterized protein; Belongs to the SKP1 family.
    
 
 0.918
H2Y8C4_CIOSA
V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.
    
 
 0.909
H2YK91_CIOSA
V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
    
 
 0.897
H2YME0_CIOSA
Uncharacterized protein.
   
 
 0.887
H2ZB28_CIOSA
Amidohydro-rel domain-containing protein.
    
 
 0.883
H2ZNA5_CIOSA
V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
    
 
 0.865
H2YM90_CIOSA
TPR_REGION domain-containing protein.
    
   0.733
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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