Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
H2YXL3_CIOSAVacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (183 aa)    
Predicted Functional Partners:
H2ZLG3_CIOSA
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.999
H2ZQK0_CIOSA
Uncharacterized protein.
   
 0.999
H2ZNJ0_CIOSA
PX domain-containing protein.
   
 0.994
H2YPB7_CIOSA
Uncharacterized protein.
   
 
 0.989
H2Z5C4_CIOSA
Rab-GAP TBC domain-containing protein.
    
 
 0.987
H2Z6Y1_CIOSA
Uncharacterized protein.
    
 
 0.986
H2Y4W3_CIOSA
PX domain-containing protein.
   
 
 0.982
H2ZDV3_CIOSA
Uncharacterized protein.
    
 
 0.982
H2YTG0_CIOSA
UDENN domain-containing protein.
  
 
 0.981
H2YR40_CIOSA
Uncharacterized protein.
    
 
 0.972
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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