STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2YY74_CIOSAUncharacterized protein. (222 aa)    
Predicted Functional Partners:
H2YRD4_CIOSA
VWFA domain-containing protein.
   
 
 0.939
H2YBF8_CIOSA
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 0.852
H2YH26_CIOSA
PPIase FKBP-type domain-containing protein.
    
 
 0.832
H2YR72_CIOSA
Uncharacterized protein.
    
 0.787
H2YB50_CIOSA
PCI domain-containing protein.
    
 0.762
H2YTG5_CIOSA
MPN domain-containing protein.
    
 0.761
H2ZCZ9_CIOSA
RPN13_C domain-containing protein.
     
 0.742
H2ZHE4_CIOSA
Uncharacterized protein.
    
   0.741
H2Y4S5_CIOSA
AAA domain-containing protein; Belongs to the AAA ATPase family.
    
  0.733
H2Y7J4_CIOSA
Proteasome endopeptidase complex; Belongs to the peptidase T1A family.
    
  0.733
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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