STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2YY74_CIOSAUncharacterized protein. (222 aa)    
Predicted Functional Partners:
H2YRD4_CIOSA
VWFA domain-containing protein.
   
 0.898
H2YR72_CIOSA
Uncharacterized protein.
    
 0.839
H2Y9I4_CIOSA
AN1-type domain-containing protein.
    
 0.807
H2YVF2_CIOSA
Uncharacterized protein.
    
 0.766
H2Z480_CIOSA
Uncharacterized protein.
    
 0.753
H2YAB2_CIOSA
Ubiquitin-like domain-containing protein.
    
 0.741
H2YAS0_CIOSA
Uncharacterized protein.
     
 0.669
H2YBF8_CIOSA
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
  0.664
H2YVU9_CIOSA
AAA domain-containing protein; Belongs to the AAA ATPase family.
    
 0.644
H2YEJ4_CIOSA
AAA domain-containing protein; Belongs to the AAA ATPase family.
    
  0.638
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.