Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2Z1A6_CIOSAUncharacterized protein. (481 aa)    
Predicted Functional Partners:
H2Y6N5_CIOSA
Uncharacterized protein.
    
 0.802
H2ZER6_CIOSA
Fork-head domain-containing protein.
    
 0.621
H2ZF65_CIOSA
ATP-grasp domain-containing protein.
     
  0.589
H2Z148_CIOSA
Uncharacterized protein.
   
  0.582
H2ZDH8_CIOSA
Uncharacterized protein; Belongs to the NDK family.
    
 0.558
MED8
Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.543
H2YPK1_CIOSA
Uncharacterized protein.
    
 0.529
H2Y4Q9_CIOSA
Tudor domain-containing protein.
    
 0.523
H2ZK16_CIOSA
Uncharacterized protein.
    
  0.514
H2ZK25_CIOSA
Uncharacterized protein.
    
  0.514
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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