Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2Z1K6_CIOSADNA ligase. (854 aa)    
Predicted Functional Partners:
H2ZBQ2_CIOSA
Uncharacterized protein.
   
 0.999
H2YVA1_CIOSA
Uncharacterized protein.
   
 0.994
H2Y640_CIOSA
Uncharacterized protein.
   
 
 0.992
H2Y8Q5_CIOSA
SAP domain-containing protein.
   
 0.989
H2ZDZ7_CIOSA
Rho-GAP domain-containing protein.
   
   0.957
H2YQY6_CIOSA
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
   0.934
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.931
H2Y863_CIOSA
Poly [ADP-ribose] polymerase.
   
 
 0.897
H2YS08_CIOSA
Poly [ADP-ribose] polymerase.
   
 
 0.897
H2ZGS8_CIOSA
BRCT domain-containing protein; Belongs to the DNA polymerase type-X family.
  
 0.891
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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