| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FEN1 | H2Y4N5_CIOSA | ENSCSAVP00000017269 | ENSCSAVP00000000283 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Ku_N domain-containing protein. | 0.730 |
| FEN1 | H2Y8Q5_CIOSA | ENSCSAVP00000017269 | ENSCSAVP00000001703 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | SAP domain-containing protein. | 0.783 |
| FEN1 | H2YVA1_CIOSA | ENSCSAVP00000017269 | ENSCSAVP00000009261 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.461 |
| FEN1 | H2Z1K6_CIOSA | ENSCSAVP00000017269 | ENSCSAVP00000011468 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.887 |
| FEN1 | H2Z3I5_CIOSA | ENSCSAVP00000017269 | ENSCSAVP00000012147 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. | 0.989 |
| FEN1 | H2ZBQ2_CIOSA | ENSCSAVP00000017269 | ENSCSAVP00000015017 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.842 |
| FEN1 | H2ZGS8_CIOSA | ENSCSAVP00000017269 | ENSCSAVP00000016794 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | BRCT domain-containing protein; Belongs to the DNA polymerase type-X family. | 0.930 |
| FEN1 | H2ZPN4_CIOSA | ENSCSAVP00000017269 | ENSCSAVP00000019550 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.868 |
| H2Y4N5_CIOSA | FEN1 | ENSCSAVP00000000283 | ENSCSAVP00000017269 | Ku_N domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.730 |
| H2Y4N5_CIOSA | H2Y8Q5_CIOSA | ENSCSAVP00000000283 | ENSCSAVP00000001703 | Ku_N domain-containing protein. | SAP domain-containing protein. | 0.999 |
| H2Y4N5_CIOSA | H2Y9G7_CIOSA | ENSCSAVP00000000283 | ENSCSAVP00000001965 | Ku_N domain-containing protein. | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. | 0.878 |
| H2Y4N5_CIOSA | H2YVA1_CIOSA | ENSCSAVP00000000283 | ENSCSAVP00000009261 | Ku_N domain-containing protein. | Uncharacterized protein. | 0.646 |
| H2Y4N5_CIOSA | H2Z1K6_CIOSA | ENSCSAVP00000000283 | ENSCSAVP00000011468 | Ku_N domain-containing protein. | DNA ligase. | 0.921 |
| H2Y4N5_CIOSA | H2Z3I5_CIOSA | ENSCSAVP00000000283 | ENSCSAVP00000012147 | Ku_N domain-containing protein. | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. | 0.731 |
| H2Y4N5_CIOSA | H2ZBQ2_CIOSA | ENSCSAVP00000000283 | ENSCSAVP00000015017 | Ku_N domain-containing protein. | Uncharacterized protein. | 0.654 |
| H2Y4N5_CIOSA | H2ZGS8_CIOSA | ENSCSAVP00000000283 | ENSCSAVP00000016794 | Ku_N domain-containing protein. | BRCT domain-containing protein; Belongs to the DNA polymerase type-X family. | 0.837 |
| H2Y4N5_CIOSA | H2ZPN4_CIOSA | ENSCSAVP00000000283 | ENSCSAVP00000019550 | Ku_N domain-containing protein. | Uncharacterized protein. | 0.830 |
| H2Y4N5_CIOSA | H2ZQ34_CIOSA | ENSCSAVP00000000283 | ENSCSAVP00000019700 | Ku_N domain-containing protein. | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | 0.991 |
| H2Y8Q5_CIOSA | FEN1 | ENSCSAVP00000001703 | ENSCSAVP00000017269 | SAP domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.783 |
| H2Y8Q5_CIOSA | H2Y4N5_CIOSA | ENSCSAVP00000001703 | ENSCSAVP00000000283 | SAP domain-containing protein. | Ku_N domain-containing protein. | 0.999 |