STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2Z1K6_CIOSADNA ligase. (854 aa)    
Predicted Functional Partners:
H2ZBQ2_CIOSA
Uncharacterized protein.
   
 0.995
H2Z3I5_CIOSA
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
  
 
 0.980
H2Y8Q5_CIOSA
SAP domain-containing protein.
   
 0.929
H2Y4N5_CIOSA
Ku_N domain-containing protein.
   
 0.921
H2YVA1_CIOSA
Uncharacterized protein.
   
 0.907
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.887
H2ZGS8_CIOSA
BRCT domain-containing protein; Belongs to the DNA polymerase type-X family.
  
 0.837
H2ZPN4_CIOSA
Uncharacterized protein.
  
 0.836
H2ZQ34_CIOSA
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.807
H2Y9G7_CIOSA
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
   
 0.798
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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