STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2Z3G3_CIOSAPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (938 aa)    
Predicted Functional Partners:
H2YBY7_CIOSA
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.908
H2YMY6_CIOSA
Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
  
0.844
H2YI37_CIOSA
Uncharacterized protein.
    
  0.795
H2Z3V7_CIOSA
Uncharacterized protein.
    
  0.795
H2Y4R2_CIOSA
Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
     
 0.764
H2YK68_CIOSA
S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling. Acts as a sensor of S-adenosyl-L- methionine to signal methionine sufficiency to mTORC1. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.
    
 0.750
H2YHW2_CIOSA
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
 0.741
H2YIF9_CIOSA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
     
 0.738
H2YQJ2_CIOSA
Uncharacterized protein; Belongs to the calmodulin family.
    
 0.723
H2YYC3_CIOSA
Uncharacterized protein.
    
 0.723
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.