STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2ZHR4_CIOSAHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (231 aa)    
Predicted Functional Partners:
H2Y4Q9_CIOSA
Tudor domain-containing protein.
    
 0.939
H2ZA69_CIOSA
Histone H2A; Belongs to the histone H2A family.
 
 0.914
H2YRA0_CIOSA
Uncharacterized protein.
    
 
 0.887
H2YC62_CIOSA
Uncharacterized protein.
    
 0.882
H2ZD31_CIOSA
Histone H2A; Belongs to the histone H2A family.
 
 
 0.874
H2YBL1_CIOSA
Uncharacterized protein.
   
 0.867
H2Z087_CIOSA
WD_REPEATS_REGION domain-containing protein.
    
 0.858
H2Y6U5_CIOSA
PH domain-containing protein.
   
 0.855
H2ZHA7_CIOSA
Uncharacterized protein.
    
 0.854
H2Z2H0_CIOSA
Uncharacterized protein.
    
 0.847
Your Current Organism:
Ciona savignyi
NCBI taxonomy Id: 51511
Other names: C. savignyi, Pacific transparent sea squirt, transparent tunicate
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.